DermTV – Hyaluronic Acid as Filler and Moisturizer [ Epi #269]

DermTV – Hyaluronic Acid as Filler and Moisturizer [ Epi #269]

Hello, I’m Dr. Neal Schultz [pause] and welcome to DermTV. Today I’d like to tell you about hyaluronic
acid, one of my favorite skin care ingredients. And the reason it’s one
of my favorites is because it’s so important both on the surface of the skin
and inside the skin. On the surface of the skin it, is a great humectant
ingredient in moisturizers, so it makes moisturizers work very well. Humectants
are simply materials that retain moisture and the reason hyaluronic
acid is such a great moisturizer is because it holds so much water because
it is a very, very long molecule, longer than most humectants and as a result
there are a lot of different interstites or little spaces in that molecule
where it can hold water, so it just holds lots and lots of water. But
in reality, we don’t normally find hyaluronic acid on the surface of the
skin, we normally find it in the dermis inside the skin in the second layer
and inside the dermis of the skin, it’s this pink material, in that pink
material you have a lot of hyaluronic acid and a lot of water. Well because
the hyaluronic acid binds water, it binds it very well there so it forms
a lot of volume and that volume helps support the collagen fibrals
and all of the organs and it’s very important in maintaining the volume of
the dermis. Anything that maintains volume here helps prevent lines
and wrinkles up here. As we get older we normally lose collagen and hyaluronic
acid both as a function of age and also as a function of sun damage.
And as a result, lines and wrinkles form because this area contracts
and everything falls in. So, hyaluronic acid is a very valuable ingredient
in filler materials that dermatologists use to inject into the skin
to help restore volume and thereby fix lines and wrinkles. But here’s
the catch, for the same reason that hyaluronic acid is such a good moisturizer
because it holds onto so much water, and for the same reason it’s
such a good filler material, you can’t get it into your skin by rubbing it
into your skin to fix lines and wrinkles because that molecule is just much,
much too big. So, while I encourage you to look for moisturizers with
hyaluronic acid in them as ingredients, enjoy your hyaluronic acid as
a topical moisturizer but if you want it to fix lines and wrinkles, you’ll
have to see your dermatologist.

About the Author: Earl Hamill


  1. Does hyaluronic acid (as a moisturizer) interfere with retin-a if used at the exact same time? I've heard of people layering the two to minimize the side effects of retinoids.

  2. I believe CeraVe lotion has hyaluronic acid. I've been looking for it but haven't found it locally. I still need to check Walgreens…
    I'm disappointed to hear (but glad to be informed) about how it works and how doesn't work. Sounds like either way it's still a good way to moisturize.

  3. Just wanted to say again how helpful these videos are. I was one of your patients for many years and always appreciated how well you advised and informed (as well as cured!) It's fun to see you again online. (I no longer live in NY but would recommend you as a dermatologist to anyone who does!)

  4. @ilthemsc try Cera-ve. it has really been doing good for me, and I used to have the same problems as you. I used proactiv for 4 years and now use a Rx 5% BP wash in the day, and 2.5% Proactiv topical lotion after that and my skin is still nicely moisturized. i've also tried Clinique dramatically different gel and lotion, but I still recommend Cera-ve because its more affordable, find it @ walmart and I believe works better! and the best part is, it doesn't clog pores/cause pimples 🙂 good luck!

  5. dang, the end just ruined hopes for me 🙁 i need something to fill my two nasty lines of deep-set wrinkles on my forehead and I only just turned 20!

  6. thank you for help us to choose the right tings, now before buy a new product I make first a research on your channel for being sure that I will get the right product that I really need. Infact I have started with hyaluronic acid fillers for correcting my assimetric lips and I have to tell that I feel much better now. Thanks again for your helpfully videos (sorry for my bad english)

  7. Hello, I have very oily skin, but yet sometimes is dehydrated, would pure hyaluronic acid be a good moisturizer for me. I'm not looking for a wrinkle reducer, but just a moisturizer for my oil skin.

  8. Hi Doc,

    Just want to ask you, if I have a Hyaluronic Acid (Ampoule Filler), do I need to apply another layer of moisturer?

    if I need to apply another layer of moisturer, do I apply the moisturer before or after applying Hyaluronic Acid (Ampoule Filler)?

  9. @aimesbegonia, all cera-ve has Hyaluronic Acid.

    For example, facial moisturizer PM ingredient list:
    Purified Water, Glycerin, Caprylic/Capric Triglycerides, Niacinamide, Behentrimonium Methosulfate And Cetearyl Alcohol, Ceteareth-20 And Cetearyl Alcohol, Ceramide 3, Ceramide 6-II, Ceramide 1, Phytosphingosine, Hyaluronic Acid, Cholesterol, Dimethicone, Polyglyceryl-3 Diisostearate, Potassium Phosphate, Sodium Lauryl Lactylate, Disodium EDTA, Methylparaben, Propylparaben, Carbomer, Xanthan Gum.

  10. Hello,

    So moiturisers with Hyaluronic Acid cant remove the wrinkles? Should someone intake like eat Hyaluronic Acid to help with the wrinkls? Im a bit confused! Thnks!

  11. pills get digested bro. our guts are made to eat up the compound as it's present in alot of our food as alot of animals use the same compound. basically why pill it.

    improving the ability to produce it in connective tissue cells in the dermis would be much better solution. as in old age your body is denying you of the production of such materials as is. they would be converted into other compounds or base compounds in the liver.

  12. thank you for the info. what is the molecular weight of the Hyaluronic Acid powder that is best to use in diy serums? i mean in daltons.
    and is it best to combine low molecular weight powder with high molecular weight powder for best results in the diy, and if so, which molecular weight should it be of each?

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